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			A 57-year-old man with leukocytosis and sphenoid sinus disease 
  Digital Journal of Ophthalmology 2020Volume 26, Number 2
 April 24, 2020
 DOI: 10.5693/djo.03.2019.09.003
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			Ansuya P. Deosaran, MD | Department of Ophthalmology, Louisiana State University, New Orleans, Louisiana Ahmaida Zeglam, MD | Department of Ophthalmology, University of Florida, Gainesville, Florida Mary K. Wilson, BS | College of Medicine, University of Florida, Gainesville, FloridaAndres Gonzalez, MD  | Department of Ophthalmology, University of Florida, Gainesville, Florida Matthew J. Gray, MD | Department of Ophthalmology, University of Florida, Gainesville, Florida 
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		|  |  | Differential Diagnosis |  | The differential diagnosis for invasive fungal sinusitis includes an infection with Aspergillus, Rhizopus, Mucorales, Fusarium, and dematiaceous fungi.(1,2). These fungi cause tissue necrosis, vascular thrombosis, and infarction (2). Among these, the most likely fungi are Aspergillus and Rhizopus species.(2) Identification of the organism is made with culture, immunohistochemistry, and in situ hybridization.(2,3) |  |  |  |  |   
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